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Immunogen sequence: MDSVEKGAAT SVSNPRGRPS RGRPPKLQRN SRGGQGRGVE KPPHLAALIL ARGGSKGIPL KNIKHLAGVP LIGWVLRAAL DSGAFQSVWV STDHDEIENV AKQFGAQVHR RSSEVSKDSS TSLDAIIEFL NYHNEVDIVG NIQATSPCLH PTDLQKVAEM IREEGYDSVF SVVRRHQFRW SEIQKGVREV TEPLNLNPAK RPRRQDWDGE LYENGSFYFA KRHLIEMGYL QGGKMAYYEM RAEHSVDIDV DIDWPIAEQR VLR; Positive Samples: U-87MG, HT-29, 293T, HepG2, DU145, Mouse heart, Rat liver; Cellular Location: Nucleus
Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CMP-N-acetylneuraminic acid synthase; CMP-N-acetylneuraminic acid synthetase; CMP-Neu5Ac synthase; CMP-Neu5Ac synthetase; CMP-NeuNAc synthase; CMP-NeuNAc synthetase; CMP-sialic acid synthetase; cytidine 5'-monophosphate N-acetylneuraminic acid synthetase; cytidine monophospho-N-acetylneuraminic acid synthetase; N-acylneuraminate cytidylyltransferase
Gene Aliases: AW208911; CMAS; CMPNeu5Ac; CSS; D6Bwg0250e
UniProt ID: (Human) Q8NFW8, (Mouse) Q99KK2
Entrez Gene ID: (Human) 55907, (Rat) 312826, (Mouse) 12764
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