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CMBL Antibody (PA5-143929) in IHC (P)
Immunohistochemistry analysis of CMBL in paraffin-embedded section of human colorectal cancer tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. Samples were incubated with CMBL Polyclonal antibody (Product # PA5-143929) using a dilution of 2 μg/mL overnight at 4°C. Biotinylated goat anti-rabbit IgG w... View More
Product Details
PA5-143929
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human LOC134147/CMBL recombinant protein (Position: M1-M246).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.01mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_3075143
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human K562 whole cell, human PC-3 whole cell, human HepG2 whole cell, human HEK293 whole cell, human A549 whole cell, human U87 whole cell, rat liver tissue, rat kidney tissue, mouse kidney tissue. IHC: human adnexal serous adenocarcinoma tissue, human lung cancer tissue, human colorectal cancer tissue. Flow: U20S cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
CMBL is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ab2-225; Carboxymethylenebutenolidase homolog; carboxymethylenebutenolidase homolog (Pseudomonas); carboxymethylenebutenolidase-like (Pseudomonas); Liver regeneration-related protein LRRG072
Gene Aliases: 2310016A09Rik; Ab2-225; CMBL; JS-1; RGD1306952
UniProt ID: (Human) Q96DG6, (Rat) Q7TP52, (Mouse) Q8R1G2
Entrez Gene ID: (Human) 134147, (Rat) 310201, (Mouse) 69574
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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