Invitrogen

COL11A2 Polyclonal Antibody

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COL11A2 Antibody (PA5-116517) in WB

Western blot analysis of COL11A2 in extracts of various cell lines. Samples were incubated with COL11A2 Polyclonal antibody (Product # PA5-116517) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

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产品信息

PA5-116517

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 210-380 of human COL11A2 (NP_5424112)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.49 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2901148

产品详细信息

Positive Samples: A375, HepG2, K-562

Immunogen sequence: IVPGVQAAYE SCEQKELECE GGQRERPQNQ QPHRAQRSPQ QQPSRLHRPQ NQEPQSQPTE SLYYDYEPPY YDVMTTGTTP DYQDPTPGEE EEILESSLLP PLEEEQTDLQ VPPTADRFQA EEYGEGGTDP PEGPYDYTYG YGDDYREETE LGPALSAETA HSGAAAHGPR G

靶标信息

This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.

仅用于科研。不用于诊断过程。未经明确授权不得转售。