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COL9A1 Antibody (PA5-103380) in IHC (P)
Immunohistochemistry analysis of COL9A1 in rat testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with COL9A1 polyclonal antibody (Product # PA5-103380) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-103380
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human COL9A1(Accession P20849), corresponding to amino acid residues G424-T474.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852724
产品详细信息
Antibody detects endogenous levels of total Collagen IX alpha 1.
靶标信息
COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha 1 type IX collagen; alpha-1(IX) collagen chain; cartilage-specific short collagen; Collagen alpha-1(IX) chain; collagen IX, alpha-1 polypeptide; collagen, type IX, alpha 1; procollagen, type IX, alpha 1
基因别名: Col9a-1; COL9A1; DJ149L1.1.2; EDM6; MED; STL4
UniProt ID: (Human) P20849, (Mouse) Q05722
Entrez Gene ID: (Human) 1297, (Mouse) 12839
