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COL9A1 Antibody (PA5-93062) in WB
Western blot analysis of COL9A1 in extracts of various cell lines. Samples were incubated with COL9A1 Polyclonal antibody (Product # PA5-93062) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-93062
应用
建议稀释比
已发表文章
产品规格
种属反应
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 20-270 of human COL9A1 (NP_0018423)
偶联物
形式
Liquid
浓度
1.09 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806609
产品详细信息
Immunogen sequence: WASAAVKRRP RFPVNSNSNG GNELCPKIRI GQDDLPGFDL ISQFQVDKAA SRRAIQRVVG SATLQVAYKL GNNVDFRIPT RNLYPSGLPE EYSFLTTFRM TGSTLKKNWN IWQIQDSSGK EQVGIKINGQ TQSVVFSYKG LDGSLQTAAF SNLSSLFDSQ WHKIMIGVER SSATLFVDCN RIESLPIKPR GPIDIDGFAV LGKLADNPQV SVPFELQWML IHCDPLRPRR ETCHELPARI TPSQTTDERG P; Positive Samples: Mouse skeletal muscle; Cellular Location: extracellular matrix, extracellular space
靶标信息
COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: collagen alpha-1(IX) chain; procollagen, type IX, alpha 1
Entrez Gene ID: (Rat) 305104
