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Invitrogen
COLEC12 Polyclonal Antibody
Product Details
PA5-30835
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 140 and 433 of Human Colec12
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2548309
Product Specific Information
Recommended positive controls: Raji, K562.
Predicted reactivity: Mouse (92%), Rat (91%), Chicken (83%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CL-P1; Collectin placenta protein 1; collectin sub-family member 12; Collectin-12; hCL-P1; Nurse cell scavenger receptor 2; Scavenger receptor class A member 4; scavenger receptor class A, member 4; Scavenger receptor with C-type lectin
Gene Aliases: CLP1; COLEC12; NSR2; SCARA4; SRCL
UniProt ID: (Human) Q5KU26, (Rat) Q4V885
Entrez Gene ID: (Human) 81035, (Rat) 361289
receptor-mediated endocytosis
phagocytosis, recognition
defense response
carbohydrate mediated signaling
toll-like receptor 3 signaling pathway
innate immune response
protein homooligomerization
positive regulation of cell adhesion molecule production
cellular response to exogenous dsRNA
pattern recognition receptor signaling pathway
immune response
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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