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产品信息
PA5-30835
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 140 and 433 of Human Colec12
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548309
产品详细信息
Recommended positive controls: Raji, K562.
Predicted reactivity: Mouse (92%), Rat (91%), Chicken (83%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CL-P1; Collectin placenta protein 1; collectin sub-family member 12; Collectin-12; hCL-P1; Nurse cell scavenger receptor 2; Scavenger receptor class A member 4; scavenger receptor class A, member 4; Scavenger receptor with C-type lectin
基因别名: CLP1; COLEC12; NSR2; SCARA4; SRCL
UniProt ID: (Human) Q5KU26, (Rat) Q4V885
Entrez Gene ID: (Human) 81035, (Rat) 361289
receptor-mediated endocytosis
phagocytosis, recognition
defense response
carbohydrate mediated signaling
toll-like receptor 3 signaling pathway
innate immune response
protein homooligomerization
positive regulation of cell adhesion molecule production
cellular response to exogenous dsRNA
pattern recognition receptor signaling pathway
immune response
