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COLEC12 Antibody (PA5-87886) in WB
Western blot analysis of COLEC12 in extracts of various cell lines. Samples were incubated with COLEC12 Polyclonal antibody (Product # PA5-87886) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-87886
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of human COLEC12 (NP_5690571)
偶联物
形式
Liquid
浓度
1.48 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804480
产品详细信息
Immunogen sequence: KVVEKMDNVT GGMETSRQTY DDKLTAVESD LKKLGDQTGK KAISTNSELS TFRSDILDLR QQLREITEKT SKNKDTLEKL QASGDALVDR QSQLKETLEN NSFLITTVNK TLQAYNGYVT NLQQDTSVLQ GNLQNQMYSH NVVIMNLNNL NLTQVQQRNL ITNLQRSVDD TSQAIQRIKN DFQNLQQVFL QAKKDTDWLK EKVQSLQTLA A; Positive Samples: A-549, U-87MG, 293T, Mouse lung, Mouse liver; Cellular Location: Membrane, Single-pass type II membrane protein
靶标信息
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CL-P1; Collectin placenta protein 1; collectin sub-family member 12; Collectin-12; hCL-P1; Nurse cell scavenger receptor 2; Scavenger receptor class A member 4; scavenger receptor class A, member 4; Scavenger receptor with C-type lectin
基因别名: CL-P1; CLP1; COLEC12; NSR2; SCARA4; SRCL
UniProt ID: (Human) Q5KU26, (Mouse) Q8K4Q8
Entrez Gene ID: (Human) 81035, (Mouse) 140792
receptor-mediated endocytosis
phagocytosis, recognition
defense response
carbohydrate mediated signaling
toll-like receptor 3 signaling pathway
innate immune response
protein homooligomerization
positive regulation of cell adhesion molecule production
cellular response to exogenous dsRNA
pattern recognition receptor signaling pathway
immune response
