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产品信息
H00001311-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
COMP (ABM87644.1, 1 a.a. approximately 724 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLRELQETNA ALQDVRELLR QQVREITFLK NTVMECDACG MQQSVRTGLP SVRPLLHCAP GFCFPGVACI QTESGARCGP CPAGFTGNGS HCTDVNECNA HPCFPRVRCI NTSPGFRCEA CPPGYSGPTH QGVGLAFAKA NKQVCTDINE CETGQHNCVP NSVCINTRGS FQCGPCQPGF VGDQASGCQR RAQRFCPDGS PSECHEHADC VLERDGSRSC VCAVGWAGNG ILCGRDTDLD GFPDEKLRCP ERQCRKDNCV TVPNSGQEDV DRDGIGDACD PDADGDGVPN EKDNCPLVRN PDQRNTDEDK WGDACDNCRS QKNDDQKDTD QDGRGDACDD DIDGDRIRNQ ADNCPRVPNS DQKDSDGDGI GDACDNCPQK SNPDQADVDH DFVGDACDSD QDQDGDGHQD SRDNCPTVPN SAQEDSDHDG QGDACDDDDD NDGVPDSRDN CRLVPNPGQE DADRDGVGDV CQDDFDADKV VDKIDVCPEN AEVTLTDFRA FQTVVLDPEG DAQIDPNWVV LNQGREIVQT MNSDPGLAVG YTAFNGVDFE GTFHVNTVTD DDYAGFIFGY QDSSSFYVVM WKQMEQTYWQ ANPFRAVAEP GIQLKAVKSS TGPGEQLRNA LWHTGDTESQ VRLLWKDPRN VGWKDKKSYR WFLQHRPQVG YIRVRFYEGP ELVADSNVVL DTTMRGGRLG VFCFSQENII WANLRYRCND TIPEDYETHQ LRQA
靶标信息
COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cartilage oligomeric matrix protein; cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple); cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple); COMP; MGC131819; MGC149768; pseudoachondroplasia (epiphyseal dysplasia 1, multiple); Thrombospondin-5; Thrombospondin5; TSP 5; TSP5
基因别名: COMP; EDM1; EPD1; MED; PSACH; THBS5; TSP5
UniProt ID: (Human) P49747
Entrez Gene ID: (Human) 1311
