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产品信息
PA5-96435
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human COMP (NP_0000862)
偶联物
形式
Liquid
浓度
2.36 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808237
产品详细信息
Immunogen sequence: GQGQSPLGSD LGPQMLRELQ ETNAALQDVR ELLRQQVREI TFLKNTVMEC DACGMQQSVR TGLPSVRPLL HCAPGFCFPG VACIQTESGA RCGPCPAGFT GNGSHCTDVN ECNAHPCFPR VRCINTSPGF RCEACPPGYS G; Positive Samples: SW620, U-251MG, HepG2, MCF7, Mouse skeletal muscle; Cellular Location: extracellular matrix, extracellular space
靶标信息
COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cartilage oligomeric matrix protein; cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple); cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple); COMP; MGC131819; MGC149768; pseudoachondroplasia (epiphyseal dysplasia 1, multiple); Thrombospondin-5; Thrombospondin5; TSP 5; TSP5
基因别名: COMP; EDM1; EPD1; MED; PSACH; THBS5; TSP5
UniProt ID: (Human) P49747, (Mouse) Q9R0G6, (Rat) P35444
Entrez Gene ID: (Human) 1311, (Mouse) 12845, (Rat) 25304
