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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human COMP/THBS5.
COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cartilage oligomeric matrix protein; cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple); cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple); COMP; MGC131819; MGC149768; pseudoachondroplasia (epiphyseal dysplasia 1, multiple); Thrombospondin-5; Thrombospondin5; TSP 5; TSP5
基因别名: COMP; EDM1; EPD1; MED; PSACH; THBS5; TSP5
UniProt ID: (Human) P49747
Entrez Gene ID: (Human) 1311