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Immunogen sequence: ALKHALHCTI LASAGQQRSR MLATLFKDER CQQLAAYGIL EKMYLDRIIR GNQLQEFAAM LMPHQKATTA DGSSILDRAV IEHNLLSASK LY
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: COP9 (constitutive photomorphogenic) homolog, subunit 4; COP9 constitutive photomorphogenic homolog subunit 4; COP9 constitutive photomorphogenic-like protein subunit 4; COP9 signalosome complex subunit 4; JAB1-containing signalosome subunit 4; SGN4; signalosome subunit 4; testis tissue sperm-binding protein Li 42a
基因别名: COPS4; CSN4
UniProt ID: (Human) Q9BT78, (Rat) Q68FS2
Entrez Gene ID: (Human) 51138, (Rat) 360915