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产品信息
PA5-60591
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2640087
产品详细信息
Immunogen sequence: DKPVIGISTY NIVPFEAGQY FNKIQCFCFE EQRLNPQEEV DMPVFFYIDP EFAEDPRMIK VDLITLSYTF FEAKEGHKLP VPG
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
靶标信息
Cytochrome c oxidase (COX) is the terminal enzyme in the electron transfer chain, functioning as a transmembrane proton pump that builds an electrochemical gradient with chemical energy from the reduction of O2. Cytochrome c oxidase assembly protein COX11 is an intracellular mitochondrial membrane protein necessary for the construction of an active COX complex. COX11 contains a single transmembrane helix downstream of the N-terminal, mitochondrial targeting sequence and a C-terminal Cu(I)-binding domain. The assembly of COX requires the delivery of metal cofactors. Along with COX12 and SCO1/2, COX11 acts as a metal ion chaperone necessary for copper insertion into CuA and CuB redox-active copper centers of COX in eukaryotes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: COX11 cytochrome c oxidase copper chaperone; COX11 homolog, cytochrome c oxidase assembly protein; Cytochrome c oxidase assembly protein COX11, mitochondrial; cytochrome c oxidase subunit 11
基因别名: COX11; COX11P
UniProt ID: (Human) Q9Y6N1
Entrez Gene ID: (Human) 1353
