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COX5A Antibody (459120) in ICC/IF
Immunofluorescent analysis of Complex IV in MRC5 cells using a Complex IV Monoclonal antibody (Product # 459120) at a concentration of 10 µg/mL. Cultured Human embryonic lung-derived fibroblasts (strain MRC5) were fixed, treated for heat-induced antigen retrieval, permeabilized, and then labeled with Complex IV Monoclonal antibody (Product # 459120) at a concentration of 10 µg/mL. An AlexaFluor® 488-conjugated-goat-anti-mouse IgG2a isotype specific secondary antibody at a concentration of 1 µg/mL was used for detection.
产品信息
459120
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
6E9B12D5
抗原
Bovine COX5A
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
HEPES buffered saline
内含物
0.02% sodium azide
保存条件
4° C, do not freeze
运输条件
Wet ice
RRID
AB_10376328
产品详细信息
Positive control: Isolated mitochondria from Human heart, Bovine heart, Rat heart, Mouse heart, and HepG2, Human embryonic lung-derived fibroblasts (strain MRC5), HeLa cells.
靶标信息
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Cytochrome c oxidase polypeptide Va; cytochrome c oxidase polypeptide, mitochondrial; Cytochrome c oxidase subunit 5A, mitochondrial; cytochrome c oxidase subunit Va; mitochondrial cytochrome c oxidase subunit 5a; mitochondrial cytochrome c oxidase subunit Va
基因别名: AA959768; CcOX; COX; COX-VA; COX5A; VA
UniProt ID: (Human) P20674, (Bovine) P00426, (Rat) P11240, (Mouse) P12787
Entrez Gene ID: (Human) 9377, (Bovine) 444878, (Rat) 252934, (Mouse) 12858
