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产品信息
PA5-20561
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 14 amino acid peptide from near the amino terminus of human CPEB1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11153522
产品详细信息
A suggested positive control is rat brain tissue lysate.
PA5-20561 can be used with blocking peptide PEP-0681.
靶标信息
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the nuclear membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the nuclear membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CEBP; CPE-binding protein 1; CPE-BP1; CPEB; CPEB-1; Cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; mCPEB-1; MGC34136; MGC60106
基因别名: AU024112; CPE-BP1; CPEB; CPEB-1; CPEB1; h-CPEB; hCPEB-1; mCPEB
UniProt ID: (Human) Q9BZB8, (Mouse) P70166, (Rat) P0C279
Entrez Gene ID: (Human) 64506, (Mouse) 12877, (Rat) 293056
mRNA processing
regulation of translation
synaptonemal complex assembly
negative regulation of cell proliferation
positive regulation of neuron projection development
negative regulation of translation
positive regulation of cell migration
cellular response to insulin stimulus
positive regulation of translation
regulation of neuronal synaptic plasticity
mRNA transport
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to amino acid stimulus
cellular response to hypoxia
negative regulation of cytoplasmic translation
cellular response to lipopolysaccharide
translation
