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Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.
Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (92%), Pig (97%), Chicken (93%), Rhesus Monkey (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the nuclear membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the nuclear membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CEBP; CPE-binding protein 1; CPE-BP1; Cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; MGC34136; MGC60106
基因别名: CPE-BP1; CPEB; CPEB-1; CPEB1; h-CPEB; hCPEB-1
UniProt ID: (Human) Q9BZB8
Entrez Gene ID: (Human) 64506