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CPSF160 Antibody (IHC-00306) in IHC (P)
Detection of human CPSF160 by IHC-IF. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-CPSF160 (Product # IHC-00306) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody Hilyte Plus™ 555 used at a dilution of 1:100.
产品信息
IHC-00306
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1392 and 1442 of human cleavage and polyadenylation specific factor 1, 160kD subunit.
偶联物
形式
Liquid
浓度
0.10 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla, Naked mole rat and Chinese hamster
靶标信息
Midline-1 (Tripartite motif-containing protein 18, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1. Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation. It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Defects in MID1 are the cause of Opitz syndrome type I (OS-I). OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cleavage and polyadenylation specific factor 1, 160kDa; cleavage and polyadenylation specificity factor 1; Cleavage and polyadenylation specificity factor 160 kDa subunit; Cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; CPSF160; polyadenylation specificity factor
基因别名: CPSF1; CPSF160; HSU37012; P/cl.18
UniProt ID: (Human) Q10570, (Mouse) Q9EPU4
Entrez Gene ID: (Human) 29894, (Mouse) 94230
