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CPT1A Antibody (PA5-29995) in IHC (P)
CPT1A Polyclonal Antibody detects CPT1A protein at mitochondria by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. CPT1A stained by CPT1A Polyclonal Antibody (Product # PA5-29995) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
PA5-29995
产品规格
种属反应
Human,
Mouse
已发表种属
Rabbit
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 397 and 614 of Human CPT1A
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2547469
产品详细信息
Recommended positive controls: A549, HeLa, HepG2.
Predicted reactivity: Mouse (84%), Rat (82%), Dog (86%), Pig (89%), Sheep (85%), Bovine (86%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Carnitine O-palmitoyltransferase 1, liver isoform; Carnitine O-palmitoyltransferase I, liver isoform; carnitine palmitoyltransferase 1, liver; Carnitine palmitoyltransferase 1A; carnitine palmitoyltransferase 1A (liver); carnitine palmitoyltransferase I, liver; CPT 1; CPT I; CPT1 L; CPT1-L; CPTI-L; L-CPT I; Succinyltransferase CPT1A
基因别名: C730027G07; Cpt-1; CPT1; CPT1-L; CPT1A; CPTI; L-CPT1
UniProt ID: (Human) P50416, (Mouse) P97742
Entrez Gene ID: (Human) 1374, (Mouse) 12894
long-chain fatty acid metabolic process
glucose metabolic process
fatty acid beta-oxidation
triglyceride metabolic process
carnitine shuttle
circadian rhythm
carnitine metabolic process
response to organic cyclic compound
epithelial cell differentiation
positive regulation of fatty acid beta-oxidation
response to drug
eating behavior
regulation of insulin secretion
protein homooligomerization
cellular response to fatty acid
lipid metabolic process
fatty acid metabolic process
transport
regulation of fatty acid oxidation
