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产品信息
PA5-113298
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Cyclic AMP-responsive element-binding protein 3-like protein 1 protein (396-500AA)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2868032
靶标信息
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system. May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BBF-2 homolog; cAMP responsive element binding protein 3-like 1; cAMP-responsive element-binding protein 3-like protein 1; Cyclic AMP-responsive element-binding protein 3-like protein 1; OASIS; old astrocyte specifically induced substance; Old astrocyte specifically-induced substance
基因别名: CREB3L1; OASIS; PSEC0238
UniProt ID: (Human) Q96BA8, (Mouse) Q9Z125, (Rat) Q66HA2
Entrez Gene ID: (Human) 90993, (Mouse) 26427, (Rat) 362165
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
protein binding
cAMP response element binding
sequence-specific DNA binding
transcription regulatory region DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
osteoblast differentiation
transcription from RNA polymerase II promoter
multicellular organism development
endoplasmic reticulum unfolded protein response
extracellular matrix constituent secretion
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
transcription, DNA-templated
regulation of transcription, DNA-templated
response to unfolded protein
regulation of ossification
positive regulation of transcription from RNA polymerase II promoter
regulation of bone mineralization
