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产品信息
PA1-4325
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide: L(160) V G K A D E K A S E H H S P Q A(176)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2111614
产品详细信息
PA1-4325 detects CRG-L2 in human samples.
PA1-4325 has been successfully used in Western blotting procedures. The predicted molecular weight is 48 kDa. By Western blot, this antibody detects a protein often above ~50 kDa representing CRG-L2. This protein can form dimers.
PA1-4325 immunizing peptide corresponds to amino acid residues 160-176 of human CRG-L2.
靶标信息
CRG-L2 is a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: collomin; colmedin; FLJ23917; Gliomedin; Gliomedin shedded ectodomain
基因别名: CLOM; COLM; CRG-L2; CRGL2; GLDN; UNC-112; UNQ9339/PRO34011
UniProt ID: (Human) Q6ZMI3
Entrez Gene ID: (Human) 342035
