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CSGALNACT1 Antibody (PA5-24847) in IHC (P)
Immunohistochemistry analysis of CSGALNACT1 in formalin fixed and paraffin embedded human prostate carcinoma. Samples were incubated with CSGALNACT1 polyclonal antibody (Product # PA5-24847) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
产品信息
PA5-24847
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 192-220 amino acids from the central region of human CSGALNACT1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2542347
靶标信息
CSGALNACT1 transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). CSGALNACT1 required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. CSGALNACT1 is important role in chondroitin chain biosynthesis in cartilage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: beta1,4 N-acetylgalactosaminyltransferase; Beta4GalNAcT-1; Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1; chondroitin beta1,4 N-acetylgalactosaminyltransferase; Chondroitin sulfate N-acetylgalactosaminyltransferase 1; CsGalNAcT-1; glucuronylgalactosylproteoglycan 4-beta-N- acetylgalactosaminyltransferase
基因别名: 4732435N03Rik; beta4GalNAcT; CHGN; CSGalNAcT-1; CSGALNACT1; GALNACT1; UNQ656/PRO1287
UniProt ID: (Human) Q8TDX6, (Mouse) Q8BJQ9
Entrez Gene ID: (Human) 55790, (Mouse) 234356
acetylgalactosaminyltransferase activity
peptidoglycan glycosyltransferase activity
glucuronosyltransferase activity
metal ion binding
glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
transferase activity
glycosyltransferase
endochondral ossification
nervous system development
cell recognition
cell proliferation
anatomical structure morphogenesis
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
UDP-N-acetylgalactosamine metabolic process
proteoglycan biosynthetic process
extracellular matrix organization
chondroitin sulfate biosynthetic process
heparin biosynthetic process
UDP-glucuronate metabolic process
chondroitin sulfate proteoglycan biosynthetic process
dermatan sulfate proteoglycan biosynthetic process
chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
cartilage development
chondroitin sulfate metabolic process
