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产品信息
PA5-19062
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (CGKSLESTNVTDKD) corresponding to the internal amino acids of CSRP3 (aa 150-163).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10986955
产品详细信息
This antibody is predicted to react with bovine and canine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: cardiac LIM domain protein; Cardiac LIM protein; CRP3; Cysteine and glycine-rich protein 3; cysteine and glycine-rich protein 3 (cardiac LIM protein); Cysteine-rich protein 3; LIM domain only 4; LIM domain protein, cardiac; MGC14488; MGC61993; Muscle LIM protein; muscle lim protein isoform
基因别名: CLP; CMD1M; CMH12; CRP3; CSRP3; LMO4; MLP; MMLP
UniProt ID: (Human) P50461, (Mouse) P50462, (Rat) P50463
Entrez Gene ID: (Human) 8048, (Mouse) 13009, (Rat) 117505
blood vessel remodeling
regulation of the force of heart contraction
cardiac muscle hypertrophy
cellular calcium ion homeostasis
skeletal muscle tissue development
protein localization to organelle
detection of muscle stretch
positive regulation of transcription from RNA polymerase II promoter
cardiac muscle tissue development
cardiac myofibril assembly
cardiac muscle contraction
multicellular organism development
muscle organ development
positive regulation of myotube differentiation
cell differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
