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CSRP3 Antibody (PA5-29155) in IHC (P)
CSRP3 Polyclonal Antibody detects CSRP3 protein at cytosol on C2C12 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded C2C12 xenograft. CSRP3 Polyclonal Antibody (Product # PA5-29155) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-29155
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 194 of Human CSRP3
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2546631
Product Specific Information
Recommended positive controls: HeLa.
Predicted reactivity: Mouse (97%), Rat (95%), Pig (98%), Chicken (87%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac LIM domain protein; Cardiac LIM protein; CRP3; Cysteine and glycine-rich protein 3; cysteine and glycine-rich protein 3 (cardiac LIM protein); Cysteine-rich protein 3; LIM domain only 4; LIM domain protein, cardiac; MGC14488; MGC61993; Muscle LIM protein; muscle lim protein isoform
Gene Aliases: CLP; CMD1M; CMH12; CRP3; CSRP3; LMO4; MLP; MMLP
UniProt ID: (Human) P50461, (Mouse) P50462
Entrez Gene ID: (Human) 8048, (Mouse) 13009
blood vessel remodeling
regulation of the force of heart contraction
cardiac muscle hypertrophy
cellular calcium ion homeostasis
skeletal muscle tissue development
protein localization to organelle
detection of muscle stretch
positive regulation of transcription from RNA polymerase II promoter
cardiac muscle tissue development
cardiac myofibril assembly
cardiac muscle contraction
multicellular organism development
muscle organ development
positive regulation of myotube differentiation
cell differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
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