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CSRP3 Antibody (PA5-29155) in IHC (P)
CSRP3 Polyclonal Antibody detects CSRP3 protein at cytosol on C2C12 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded C2C12 xenograft. CSRP3 Polyclonal Antibody (Product # PA5-29155) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-29155
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 194 of Human CSRP3
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546631
产品详细信息
Recommended positive controls: HeLa.
Predicted reactivity: Mouse (97%), Rat (95%), Pig (98%), Chicken (87%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cardiac LIM domain protein; Cardiac LIM protein; CRP3; Cysteine and glycine-rich protein 3; cysteine and glycine-rich protein 3 (cardiac LIM protein); Cysteine-rich protein 3; LIM domain only 4; LIM domain protein, cardiac; MGC14488; MGC61993; Muscle LIM protein; muscle lim protein isoform
基因别名: CLP; CMD1M; CMH12; CRP3; CSRP3; LMO4; MLP; MMLP
UniProt ID: (Human) P50461, (Mouse) P50462
Entrez Gene ID: (Human) 8048, (Mouse) 13009
blood vessel remodeling
regulation of the force of heart contraction
cardiac muscle hypertrophy
cellular calcium ion homeostasis
skeletal muscle tissue development
protein localization to organelle
detection of muscle stretch
positive regulation of transcription from RNA polymerase II promoter
cardiac muscle tissue development
cardiac myofibril assembly
cardiac muscle contraction
multicellular organism development
muscle organ development
positive regulation of myotube differentiation
cell differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
