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Product Details
PA5-24695
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 767-795 amino acids from the central region of human CQ068
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2542195
Target Information
CQ068 is subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication. CQ068 also appears to function in a telomere-associated complex with OBFC1 and TEN1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: alpha accessory factor 132; conserved telomere capping protein 1; Conserved telomere maintenance component 1; CST complex subunit CTC1; HBV DNAPTP1-transactivated protein B
Gene Aliases: AAF-132; AAF132; C17orf68; CRMCC; CTC1; tmp494178
UniProt ID: (Human) Q2NKJ3
Entrez Gene ID: (Human) 80169
telomere maintenance
cellular response to DNA damage stimulus
regulation of G2/M transition of mitotic cell cycle
telomere maintenance via telomere lengthening
multicellular organism growth
positive regulation of DNA replication
positive regulation of fibroblast proliferation
spleen development
thymus development
bone marrow development
negative regulation of telomerase activity
hematopoietic stem cell proliferation
replicative senescence
regulation of telomere maintenance via telomere lengthening
Performance Guarantee
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