Invitrogen

CTGF Polyclonal Antibody, PeproTech®

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CTGF Antibody (500-P252-1MG) in WB

Western Blot: To detect Human CTGF by Western Blot analysis CTGF Polyclonal Antibody (Product # 500-P252-1MG) can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human CTGF is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

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产品信息

500-P252-1MG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1-0.2 µg/mL

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酶联免疫吸附实验 (ELISA)

0.5-2.0 µg/mL

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免疫沉淀 (IP)

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中和实验 (Neu)

- -

体外检测 (IV)

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其他PubMed (Misc)

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产品规格

种属反应

Human

已发表种属

Human, Mouse, Rat

宿主/亚型

Rabbit

分类

Polyclonal

类型

Antibody

抗原

E.coli-derived Recombinant Human CTGF

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.1-1.0 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

no preservative

保存条件

-20°C

运输条件

Ambient

AB_2930074

产品详细信息

AA Sequence of recombinant protein: GKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMA.

Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human CTGF. Anti-Human CTGF-specific antibody was purified by affinity chromatography employing an immobilized Human CTGF matrix.

Sandwich ELISA: To detect Human CTGF by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human CTGF (500-P252Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human CTGF.

Western Blot: To detect Human CTGF by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human CTGF is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

靶标信息

Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. CTGF plays important roles in the proliferation and differentiation of chondrocytes, induces angiogenesis, and promotes cell adhesion in fibroblasts, endothelial, and epithelial cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation.

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生物信息学

蛋白别名: 2-Nov; CCN family member 2; Cellular communication network factor 2; Connective tissue growth factor; H-CTGF; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; Insulin-like growth factor-binding protein 8; MGC102839

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基因别名: CCN2; CTGF; HCS24; IGFBP8; NOV2

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UniProt ID: (Human) P29279

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Entrez Gene ID: (Human) 1490

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功能

fibronectin binding integrin binding protein binding insulin-like growth factor binding protein C-terminus binding growth factor activity heparin binding growth factor

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