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产品信息
PA5-142138
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-SLYYRKMYGDMA (aa 338-349).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2932796
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:1,000.
靶标信息
Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. CTGF plays important roles in the proliferation and differentiation of chondrocytes, induces angiogenesis, and promotes cell adhesion in fibroblasts, endothelial, and epithelial cells.
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生物信息学
蛋白别名: 2-Nov; CCN family member 2; Cellular communication network factor 2; Connective tissue growth factor; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); Connective tissue growth-related protein; fibroblast inducible secreated protein; fibroblast inducible secreted protein; H-CTGF; hypertrophic chondrocyte-specific gene product 24; Hypertrophic chondrocyte-specific protein 24; MGC102839; Protein FISP-12
基因别名: betaIG-M2; Ccn2; Ctgf; CTGRP; Fisp-12; Fisp12; Hcs24
UniProt ID: (Mouse) P29268, (Rat) Q9R1E9
Entrez Gene ID: (Mouse) 14219, (Rat) 64032
cartilage condensation
ossification
angiogenesis
regulation of cell growth
tissue homeostasis
positive regulation of protein phosphorylation
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
cell-cell signaling
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of gene expression
negative regulation of gene expression
positive regulation of cell death
cell migration
cell differentiation
lung development
regulation of chondrocyte differentiation
positive regulation of collagen biosynthetic process
intracellular signal transduction
chondrocyte proliferation
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cell differentiation
positive regulation of JNK cascade
positive regulation of cell activation
positive regulation of stress fiber assembly
cytosolic calcium ion transport
positive regulation of cardiac muscle contraction
negative regulation of cell death
connective tissue development
extracellular matrix constituent secretion
positive regulation of G0 to G1 transition
positive regulation of ERK1 and ERK2 cascade
DNA biosynthetic process
reactive oxygen species metabolic process
response to glucose
organ senescence
response to organic cyclic compound
response to estradiol
response to anoxia
response to amino acid
response to peptide hormone
response to mineralocorticoid
response to fatty acid
