Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 1
CTRP5 Antibody (PA5-110379) in WB
Western blot analysis of CTRP5 in extracts of various cell lines. Samples were incubated with CTRP5 Polyclonal antibody (Product # PA5-110379) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-110379
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 16-243 of human C1QTNF5 (NP_056460.1).
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855790
产品详细信息
Immunogen sequence: SPPLDDNKIP SLCPGHPGLP GTPGHHGSQG LPGRDGRDGR DGAPGAPGEK GEGGRPGLPG PRGDPGPRGE AGPAGPTGPA GECSVPPRSA FSAKRSESRV PPPSDAPLPF DRVLVNEQGH YDAVTGKFTC QVPGVYYFAV HATVYRASLQ FDLVKNGESI ASFFQFFGGW PKPASLSGGA MVRLEPEDQV WVQVGVGDYI GIYASIKTDS TFSGFLVYSD WHSSPVFA
靶标信息
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: C1q TNF-alpha-related protein 5; Complement C1q tumor necrosis factor-related protein 5; LORD; Membrane frizzled-related protein; Membrane-type frizzled-related protein; myonectin
基因别名: C1QTNF5; CTRP5; Mfrp; UNQ303/PRO344
UniProt ID: (Human) Q9BXJ0, (Mouse) Q8K479, (Rat) Q5FVH0
Entrez Gene ID: (Human) 114902, (Mouse) 235312, (Rat) 315598
