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CTU1 Antibody (PA5-23853) in IHC (P)
Immunohistochemistry analysis of CTU1 in formalin fixed and paraffin embedded human pancreas tissue. Samples were incubated with CTU1 polyclonal antibody (Product # PA5-23853) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
产品信息
PA5-23853
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 208-236 amino acids from the central region of human ATPBD3
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2541353
产品详细信息
This antibody is predicted to react with bovine based on sequence homology.
靶标信息
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP binding domain 3; ATP-binding domain-containing protein 3; Cancer-associated gene protein; cancer-associated protein; CTU1; Cytoplasmic tRNA 2-thiolation protein 1; Cytoplasmic tRNA adenylyltransferase 1; cytosolic thiouridylase subunit 1 homolog
基因别名: ATPBD3; BC005752; CTU1; NCS6
UniProt ID: (Human) Q7Z7A3, (Mouse) Q99J10
Entrez Gene ID: (Human) 90353, (Mouse) 233189
tRNA binding
protein binding
nucleotidyltransferase activity
molecular_function
telomerase activity
RNA binding
RNA helicase activity
DNA primase activity
sulfate adenylyltransferase activity
RNA guanylyltransferase activity
tRNA guanylyltransferase activity
mannose-phosphate guanylyltransferase activity
transferase activity
DNA/RNA helicase activity
CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity
phospholactate guanylyltransferase activity
ATP:coenzyme F420 adenylyltransferase activity
UDP-N-acetylgalactosamine diphosphorylase activity
