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产品信息
PA5-96432
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-107 of human GRO alpha (NP_0015021)
偶联物
形式
Liquid
浓度
1.22 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808234
产品详细信息
Positive Samples: DU145
Immunogen sequence: MARAALSAAP SNPRLLRVAL LLLLLVAAGR RAAGASVATE LRCQCLQTLQ GIHPKNIQSV NVKSPGPHCA QTEVIATLKN GRKACLNPAS PIVKKIIEKM LNSDKSN
靶标信息
CXCL1, CXCL2, and CXCL3, also known respectively as GRO alpha, GRO beta (MIP-2 alpha) and GRO gamma (MIP-2 beta), are members of the CXC subfamily of chemokines. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 1; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); CINC-1; CXC; CXC motif chemokine; CXCL; CXCL-1; Cytokine-induced neutrophil chemoattractant 1; fibroblast secretory protein; gro; GRO a; GRO α; GRO-alpha(1-73); GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); GROalpha; Growth-regulated alpha protein; GROα; melanoma growth stimulating activity, alpha; Melanoma growth stimulatory activity; melanoma growth stimulatory activity alpha; MGSA; MGSA alpha; NAP-3; NAP3; Neutrophil-activating protein 3; Platelet-derived growth factor-inducible protein KC
基因别名: CINC-1; Cinc1; CXCL1; FSP; GRO; GRO1; GROA; MGSA; MGSA-a; NAP-3; SCYB1
UniProt ID: (Human) P09341, (Rat) P14095
Entrez Gene ID: (Human) 2919, (Rat) 81503
chemotaxis
inflammatory response
immune response
signal transduction
G-protein coupled receptor signaling pathway
nervous system development
cell proliferation
negative regulation of cell proliferation
actin cytoskeleton organization
response to lipopolysaccharide
intracellular signal transduction
positive regulation of catalytic activity
cell chemotaxis
chemokine-mediated signaling pathway
positive regulation of neutrophil chemotaxis
response to amphetamine
response to molecule of bacterial origin
acute inflammatory response
positive regulation of leukocyte chemotaxis
positive regulation of cytosolic calcium ion concentration
response to heat
response to gamma radiation
positive regulation of sodium ion transport
neutrophil chemotaxis
response to estradiol
positive regulation of superoxide anion generation
regulation of cell proliferation
positive regulation of potassium ion transport
response to glucocorticoid
positive regulation of neutrophil mediated killing of fungus
positive regulation of hematopoietic stem cell proliferation
