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CXCL11 Antibody (H00006373-D01P) in WB
Western Blot analysis of CXCL11 expression in transfected 293T cell line (H00006373-T02) by CXCL11 MaxPab polyclonal antibody.
Lane 1: CXCL11 transfected lysate(10.40 KDa).
Lane 2: Non-transfected lysate.
Lane 1: CXCL11 transfected lysate(10.40 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00006373-D01P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CXCL11 (NP_005400.1, 1 a.a. approximately 94 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MSVKGMAIAL AVILCATVVQ GFPMFKRGRC LCIGPGVKAV KVADIEKASI MYPSNNCDKI EVIITLKENK GQRCLNPKSK QARLIIKKVE RKNF
靶标信息
Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta-R1; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 11; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 11; CXC; CXC motif chemokine; CXCL; H174; I-TAC; Interferon gamma-inducible protein 9; Interferon-inducible T-cell alpha chemoattractant; IP-9; MGC102770; small inducible cytokine B11; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; Small-inducible cytokine B11
基因别名: b-R1; betaR1; Cxc11; CXCL11; H174; I-TAC; IP-9; IP9; ITAC; SCYB11; SCYB9B
UniProt ID: (Human) O14625, (Mouse) Q9JHH5
Entrez Gene ID: (Human) 6373, (Mouse) 56066
positive regulation of leukocyte chemotaxis
chemotaxis
inflammatory response
immune response
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
T cell chemotaxis
positive regulation of cAMP metabolic process
response to lipopolysaccharide
regulation of cell proliferation
positive regulation of cAMP-mediated signaling
positive regulation of release of sequestered calcium ion into cytosol
chemokine-mediated signaling pathway
cell chemotaxis
