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CXCL11 Antibody (PA5-47767) in Neu
Neutralization of CXCL11 in BaF3 mouse pro‚B cell line transfected with human CXCR3. Samples were incubated in CXCL11 polyclonal antibody (Product # PA5-47767). Recombinant MouseCXCL11/I‚TAC chemoattracts the BaF3 mouse pro‚B cell line transfected with human CXCR3 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin. Chemotaxis elicited by Recombinant Mouse CXCL11/I‚TAC (200 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-M... View More
产品信息
PA5-47767
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
已发表种属
Human,
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant mouse CXCL11/I-TAC Phe22-Met100
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2577164
产品详细信息
In sandwich ELISAs, less than 0.2% cross-reactivity with recombinant human CXCL11, recombinant mouse (rm) BLC, rmCRG-2, rmGCP-2, rmMIG, rmPF4, and rmSDF-1 alpha is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
靶标信息
Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 11; CC motif chemokine; CCmotif chemokine; CXC; CXC motif chemokine; CXCL; I-TAC; Interferon-inducible T-cell alpha chemoattractant; MGC102770; small inducible cytokine subfamily B (Cys-X-Cys), member 11; Small-inducible cytokine B11
基因别名: b-R1; betaR1; Cxc11; Cxcl11; H174; I-tac; Ip9; Itac; Scyb11; Scyb9b
UniProt ID: (Mouse) Q9JHH5
Entrez Gene ID: (Mouse) 56066
