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AA Sequence of recombinant protein: ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN.
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human GRO-gamma (CXCL3). Anti-Human GRO-gamma (CXCL3)-specific antibody was purified by affinity chromatography employing an immobilized Human GRO-gamma (CXCL3) matrix.
Sandwich ELISA: To detect Human GRO-gamma (CXCL3) by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human GRO-gamma (CXCL3) (500-P105Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human GRO-gamma (CXCL3).
Western Blot: To detect Human GRO-gamma (CXCL3) by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human GRO-gamma (CXCL3) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
CXCL3 may play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 3; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 3; CXC; CXC motif chemokine; CXCL; gro gamma; GRO-gamma; GRO-gamma(1-73); GRO3 oncogene; Growth-regulated protein gamma; Macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma; MGSA gamma; MIP2-beta
基因别名: CINC-2b; CXCL3; GRO3; GROG; MIP-2b; MIP2B; SCYB3
UniProt ID: (Human) P19876
Entrez Gene ID: (Human) 2921