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CXCL5 Antibody (MA5-23839) in Neu
Neutralization of CXCL5 in BaF3 mouse pro‚B cell line transfected with human CXCR2. Samples were incubated in CXCL5 monoclonal antibody (Product # MA5-23839). Recombinant Mouse LIX chemoattracts the BaF3 mouse pro‚B cell line transfected with human CXCR2 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin. Chemotaxis elicited by Recombinant Mouse LIX (0.2 µg/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse LIX Monoclonal ... View More
产品信息
MA5-23839
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
61905
抗原
E. coli-derived recombinant mouse LIX Val45-Ala118
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2608638
产品详细信息
In Western blots, no cross-reactivity with recombinant human CXCL1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 12/SDF-1 alpha, 12/SDF-1 beta, 13, recombinant mouse CXCL1, 2, 6, 9, 10, 12/SDF-1 alpha, 13, recombinant rat CXCL1, 3/CINC-2 alpha, 3/CINC-2 beta, or recombinant porcine CXCL8 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
靶标信息
The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 5; CC motif chemokine; CCmotif chemokine; CXC; CXC motif chemokine; CXCL; Cytokine LIX; granulocyte chemotactic protein-2; small inducible cytokine B subfamily, member 5; small inducible cytokine subfamily B, member 15; Small-inducible cytokine B5
基因别名: AMCF-II; Cxcl5; ENA-78; GCP-2; LIX; Scyb5; Scyb6
UniProt ID: (Mouse) P50228
Entrez Gene ID: (Mouse) 20311
leukocyte homeostasis
cytokine production
positive regulation of leukocyte chemotaxis
chemotaxis
inflammatory response
immune response
G-protein coupled receptor signaling pathway
positive regulation of neuron projection development
organ regeneration
response to lipopolysaccharide
regulation of chemokine production
regulation of cell proliferation
positive regulation of JAK-STAT cascade
cell chemotaxis
chemokine-mediated signaling pathway
regulation of neutrophil mediated killing of gram-negative bacterium
