Invitrogen

CYFIP1 Polyclonal Antibody

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CYFIP1 Antibody (PA5-116426) in WB

Western Blot analysis of CYFIP1 using the CYFIP1 Polyclonal Antibody (Product # PA5-116426) at a 1:2000 dilution. Lane 1: ZF4 whole cell lysates, Lane 2: Zebrafish lysates. Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10,000 dilution Predicted band size : 145 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

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产品信息

PA5-116426

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000

产品规格

种属反应

Zebrafish

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 524-558 amino acids from the Central region of DANRE cyfip1

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2901058

靶标信息

Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA. Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.

仅用于科研。不用于诊断过程。未经明确授权不得转售。