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CYP20A1 Antibody (PA5-109611) in WB
Western blot analysis of CYP20A1 in extracts of various cell lines. Samples were incubated with CYP20A1 Polyclonal antibody (Product # PA5-109611) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-109611
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 183-462 of human CYP20A1 (NP_803882.1).
偶联物
形式
Liquid
浓度
0.63 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855022
产品详细信息
Immunogen sequence: STFEDDQEVI RFQKNHGTVW SEIGKGFLDG SLDKNMTRKK QYEDALMQLE SVLRNIIKER KGRNFSQHIF IDSLVQGNLN DQQILEDSMI FSLASCIITA KLCTWAICFL TTSEEVQKKL YEEINQVFGN GPVTPEKIEQ LRYCQHVLCE TVRTAKLTPV SAQLQDIEGK IDRFIIPRET LVLYALGVVL QDPNTWPSPH KFDPDRFDDE LVMKTFSSLG FSGTQECPEL RFAYMVTTVL LSVLVKRLHL LSVEGQVIET KYELVTSSRE EAWITVSKRY
靶标信息
CYP20A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D, E)T, suggesting that its substrate may carry its own oxygen.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytochrome P450 20A1; cytochrome P450 monooxygenase; cytochrome P450, 20a1; cytochrome P450, family 20, subfamily A, polypeptide 1
基因别名: A930011N14Rik; CYP-M; CYP20A1; Cypm; UNQ667/PRO1301
UniProt ID: (Human) Q6UW02, (Mouse) Q8BKE6, (Rat) Q6P7D4
Entrez Gene ID: (Human) 57404, (Mouse) 77951, (Rat) 316435
monooxygenase activity
iron ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
heme binding
oxidoreductase activity
fluorene oxygenase activity
mono-butyltin dioxygenase activity
tri-n-butyltin dioxygenase activity
di-n-butyltin dioxygenase activity
methylsilanetriol hydroxylase activity
methyl tertiary butyl ether 3-monooxygenase activity
4-nitrocatechol 4-monooxygenase activity
4-chlorophenoxyacetate monooxygenase activity
tert-butanol 2-monooxygenase activity
alpha-pinene monooxygenase activity
dimethylsilanediol hydroxylase activity
ammonia monooxygenase activity
hydroxymethylsilanetriol oxidase activity
2-hydroxyisobutyrate 3-monooxygenase activity
alpha-pinene dehydrogenase activity
bisphenol A hydroxylase B activity
2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity
9-fluorenone-3,4-dioxygenase activity
anthracene 9,10-dioxygenase activity
2-(methylthio)benzothiazole monooxygenase activity
2-hydroxybenzothiazole monooxygenase activity
benzothiazole monooxygenase activity
2,6-dihydroxybenzothiazole monooxygenase activity
pinacolone 5-monooxygenase activity
thioacetamide S-oxygenase activity
thioacetamide S-oxide S-oxygenase activity
endosulfan monooxygenase I activity
N-nitrodimethylamine hydroxylase activity
4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity
endosulfan ether monooxygenase activity
pyrene 4,5-monooxygenase activity
pyrene 1,2-monooxygenase activity
1-hydroxypyrene 6,7-monooxygenase activity
1-hydroxypyrene 7,8-monooxygenase activity
phenylboronic acid monooxygenase activity
spheroidene monooxygenase activity
metal ion binding
oxidoreductase
oxygenase
metabolite interconversion enzyme
