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CYP24A1 Antibody (MA5-50333) in IHC (P)
Immunohistochemical analysis of CYP24A1 using CYP24A1 Recombinant Monoclonal Antibody (Product # MA5-50333) in Paraffin embedded human oral carcinoma tissue at a dilution of 1:200. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min.
Product Details
MA5-50333
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1783
Immunogen
Recombinant fragment of human CYP24A1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3094213
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1,25-@dihydroxyvitamin D3 24-hydroxylase; 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; 24-OHase; 24R-Ohase; 25-hydroxyvitamin D-24-hydroxylase; 25-hydroxyvitamin D3 24-hydroxylase; Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase); Cytochrome P450 24A1; cytochrome P450, 24; cytochrome P450, 24a1; cytochrome P450, family 24, subfamily A, polypeptide 1; cytochrome P450, subfamily 24; cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase); Cytochrome P450-CC24; exo-mitochondrial protein; MGC126273; MGC126274; P450-CC24; vitamin D 24-hydroxylase; vitamin D(3) 24-hydroxylase
Gene Aliases: 24-OHase; 25-hydroxyvitaminD324-hydroxylase; CP24; Cyp-24; CYP24; CYP24A1; HCAI; HCINF1; P450-CC24; VITD12
UniProt ID: (Human) Q07973, (Mouse) Q64441, (Rat) Q09128
Entrez Gene ID: (Human) 1591, (Mouse) 13081, (Rat) 25279
iron ion binding
25-hydroxycholecalciferol-24-hydroxylase activity
oxidoreductase activity
heme binding
1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
metal ion binding
oxygenase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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