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产品信息
PA5-30004
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 229 and 443 of Human CYP4A11
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2547478
产品详细信息
Recommended positive controls: A549, HeLa, HepG2, HCT116.
Predicted reactivity: Dog (88%), Bovine (83%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; alkane-1 monooxygenase; CYP4AII; CYPIVA11; Cytochrome P-450HK-omega; Cytochrome P450 4A11; cytochrome P450, family 4, subfamily A, polypeptide 11; cytochrome P450, subfamily IVA, polypeptide 11; Cytochrome P450HL-omega; Fatty acid omega-hydroxylase; Lauric acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase; P-450 HK omega; P450-HL-omega; P450HL-omega
基因别名: CP4Y; CYP4A11; CYP4A2; CYP4AII
UniProt ID: (Human) Q02928
Entrez Gene ID: (Human) 1579
long-chain fatty acid metabolic process
renal water homeostasis
pressure natriuresis
fatty acid metabolic process
leukotriene metabolic process
arachidonic acid metabolic process
epoxygenase P450 pathway
positive regulation of icosanoid secretion
leukotriene B4 catabolic process
sodium ion homeostasis
oxidation-reduction process
omega-hydroxylase P450 pathway
