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产品信息
PA5-97651
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Cysteinyl leukotriene receptor 1 protein (298-337AA)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2812266
靶标信息
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
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生物信息学
蛋白别名: Cys-LT1 receptor; CysLT 1; CysLT(1); CysLT1 receptor; CysLTR1; cysteinyl leukotriene 1 receptor short isoform; Cysteinyl leukotriene D4 receptor; Cysteinyl leukotriene receptor 1; G-protein coupled receptor HG55; HG55; HMTMF81; LTD4 receptor; LTD4R; MGC46139
基因别名: BB147369; CYSLT1; CYSLT1R; CYSLTR; CYSLTR1; HMTMF81
UniProt ID: (Human) Q9Y271, (Mouse) Q99JA4
Entrez Gene ID: (Human) 10800, (Mouse) 58861
circulatory system process
calcium ion transport
chemotaxis
defense response
cell surface receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
respiratory gaseous exchange
leukotriene signaling pathway
inflammatory response
signal transduction
G-protein coupled receptor signaling pathway
positive regulation of angiogenesis
positive regulation of vasoconstriction
