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产品信息
H00009266-M02
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
6H5
抗原
CYTH2 (NP_059431, 314 a.a. approximately 398 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: VDDPRKPNCF ELYIPNNKGQ LIKACKTEAD GRVVEGNHMV YRISAPTQEE KDEWIKSIQA AVSVDPFYEM LAARKKRISV KKKQE
靶标信息
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARF exchange factor; ARF nucleotide binding site opener; ARF nucleotide-binding site opener; CLM2; CTC-273B12.8; Cytohesin-2; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2); pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2); Protein ARNO; SEC7 homolog B
基因别名: ARNO; CTS18; CTS18.1; CYTH2; PSCD2; PSCD2L; Sec7; Sec7B; SEC7L; Sec7p-L; Sec7p-like
UniProt ID: (Human) Q99418, (Rat) P63035
Entrez Gene ID: (Human) 9266, (Rat) 116692
