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产品信息
PA5-109296
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within rat CaV23 aa 875-924
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2854707
产品详细信息
Positive Control: Rat brain tissue, human kidney tissue, human placenta tissue, mouse brain tissue, 293T.
靶标信息
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BII; Brain calcium channel II; Calcium channel, L type, alpha-1 polypeptide, isoform 6; calcium channel, R type, alpha-1 polypeptide, isoform 6; calcium channel, voltage-dependent, L type, alpha 1E subunit; RBE-II; RBE2; voltage gated calcium channel alpha1E subunit; voltage-dependent calcium channel alpha 1E subunit; voltage-dependent calcium channel alpha1-E subunit; Voltage-dependent R-type calcium channel subunit alpha-1E; voltage-gated calcium channel alpha subunit Cav2.3; Voltage-gated calcium channel subunit alpha Cav2.3
基因别名: BII; CACH6; CACHA1E; CACNA1E; CACNL1A6; Cav2.3; gm139
UniProt ID: (Human) Q15878
Entrez Gene ID: (Human) 777, (Rat) 54234
transport
chemical synaptic transmission
regulation of ion transmembrane transport
regulation of insulin secretion
membrane depolarization
calcium ion transmembrane transport
membrane depolarization during action potential
behavioral fear response
regulation of heart rate
calcium ion transport
locomotory behavior
visual learning
transmission of nerve impulse
sensory perception of pain
sperm motility
glucose homeostasis
fear response
response to pain
behavioral response to pain
neurological system process
regulation of insulin secretion involved in cellular response to glucose stimulus
calcium ion import
regulation of somatostatin secretion
