Invitrogen

CaV2.3 Polyclonal Antibody

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CaV2.3 Antibody (PA5-120071) in WB

Western blot analysis of CaV2.3 in extracts of various cell lines. Samples were incubated with CaV2.3 Polyclonal antibody (Product # PA5-120071) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

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产品信息

PA5-120071

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 2014-2313 of human CACNA1E (NP_001192222.1).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.67 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2913643

产品详细信息

Positive test controls include: U-87MG, 293T, Mouse brain, Mouse liver, Rat brain. The target is usually found in the following locations: Membrane, Multi-pass membrane protein.

Immunogen sequence: PSSMRRSFST IRDKRSNSSW LEEFSMERSS ENTYKSRRRS YHSSLRLSAH RLNSDSGHKS DTHRSGGRER GRSKERKHLL SPDVSRCNSE ERGTQADWES PERRQSRSPS EGRSQTPNRQ GTGSLSESSI PSVSDTSTPR RSRRQLPPVP PKPRPLLSYS SLIRHAGSIS PPADGSEEGS PLTSQALESN NACLTESSNS PHPQQSQHAS PQRYISEPYL ALHEDSHASD CGEEETLTFE AAVATSLGRS NTIGSAPPLR HSWQMPNGHY RRRRRGGPGP GMMCGAVNNL LSDTEEDDKC

靶标信息

The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: BII; Brain calcium channel II; Calcium channel, L type, alpha-1 polypeptide, isoform 6; calcium channel, R type, alpha-1 polypeptide, isoform 6; calcium channel, voltage-dependent, L type, alpha 1E subunit; RBE-II; RBE2; voltage gated calcium channel alpha1E subunit; voltage-dependent calcium channel alpha 1E subunit; voltage-dependent calcium channel alpha1-E subunit; Voltage-dependent R-type calcium channel subunit alpha-1E; voltage-gated calcium channel alpha subunit Cav2.3; Voltage-gated calcium channel subunit alpha Cav2.3

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基因别名: A430040I15; alpha1E; BII; CACH6; CACHA1E; CACNA1E; CACNL1A6; Cav2.3; Cchra1; gm139

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UniProt ID: (Human) Q15878

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Entrez Gene ID: (Human) 777, (Rat) 54234, (Mouse) 12290

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功能