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Calbindin/Calretinin is a gene target that codes for two calcium-binding proteins that are expressed in different regions of the nervous system. Calbindin is mainly found in the cerebellum, while calretinin is expressed in the hippocampus, cortex, and other brain regions. These proteins play an essential role in calcium signaling, which is crucial for neuronal function and synaptic plasticity. They are also involved in other cellular processes, such as cell survival, differentiation, and gene expression. Dysregulation of calbindin/calretinin expression has been linked to various neurological disorders, including epilepsy, Alzheimer's disease, and Parkinson's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 29 kDa calbindin; CALB1; CALB2; Calbindin; calbindin 1, (28kD); calbindin 1, 28 kD; calbindin 1, 28kDa; calbindin 2, (29kD, calretinin); Calbindin D28; calbindin D29K; calbindin-28K; calbindin-D (28k); CalbindinD28K; Calretinin; cerebellar Ca-binding protein spot 35 protein; cerebellar Ca-binding protein, spot 35 protein; CR; D-28K; PCD-29; RTVL-H protein; Spot 35 protein; testicular secretory protein Li 8; Vitamin D-dependent calcium-binding protein, avian-type
基因别名: Brain-2; CAB27; CAB29; CaBP28K; CAL2; CALB; Calb-1; CALB1; CALB2; CB; CR; D-28K
UniProt ID: (Human) P05937, (Human) P22676, (Rat) P07171, (Mouse) P12658, (Rat) P47728, (Mouse) Q08331
Entrez Gene ID: (Human) 793, (Human) 794, (Rat) 83839, (Mouse) 12307, (Rat) 117059, (Mouse) 12308