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Invitrogen
Calbindin/Calretinin Recombinant Rabbit Monoclonal Antibody (HL1787)
FIGURE: 1 / 8
Calbindin/Calretinin Antibody (MA5-50334) in ICC/IF
Immunocytochemical analysis of Calbindin/Calretinin using Calbindin/Calretinin Recombinant Monoclonal Antibody (Product # MA5-50334) in DIV9 rat E18 primary cortical neuron cells at a dilution of 1:250. Cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Calbindin stained by Calbindin antibody (MA5-50334) diluted at 1:250. Red: Tau, an axon marker, stained by Tau antibody (MA5-50334) diluted at... View More
Product Details
MA5-50334
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1787
Immunogen
Recombinant fragment of human Calbindin.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3094403
Target Information
Calbindin/Calretinin is a gene target that codes for two calcium-binding proteins that are expressed in different regions of the nervous system. Calbindin is mainly found in the cerebellum, while calretinin is expressed in the hippocampus, cortex, and other brain regions. These proteins play an essential role in calcium signaling, which is crucial for neuronal function and synaptic plasticity. They are also involved in other cellular processes, such as cell survival, differentiation, and gene expression. Dysregulation of calbindin/calretinin expression has been linked to various neurological disorders, including epilepsy, Alzheimer's disease, and Parkinson's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 29 kDa calbindin; CALB1; CALB2; Calbindin; calbindin 1, (28kD); calbindin 1, 28 kD; calbindin 1, 28kDa; calbindin 2, (29kD, calretinin); Calbindin D28; calbindin D29K; calbindin-28K; calbindin-D (28k); CalbindinD28K; Calretinin; cerebellar Ca-binding protein spot 35 protein; cerebellar Ca-binding protein, spot 35 protein; CR; D-28K; PCD-29; RTVL-H protein; Spot 35 protein; testicular secretory protein Li 8; Vitamin D-dependent calcium-binding protein, avian-type
Gene Aliases: Brain-2; CAB27; CAB29; CaBP28K; CAL2; CALB; Calb-1; CALB1; CALB2; CB; CR; D-28K
UniProt ID: (Human) P05937, (Human) P22676, (Rat) P07171, (Mouse) P12658, (Rat) P47728, (Mouse) Q08331
Entrez Gene ID: (Human) 793, (Human) 794, (Rat) 83839, (Mouse) 12307, (Rat) 117059, (Mouse) 12308
short-term memory
long-term memory
locomotory behavior
retina layer formation
metanephric part of ureteric bud development
regulation of synaptic plasticity
regulation of cytosolic calcium ion concentration
cellular response to organic substance
metanephric collecting duct development
metanephric distal convoluted tubule development
metanephric connecting tubule development
learning or memory
vitamin D metabolic process
calcium ion homeostasis
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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