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产品信息
PA5-85137
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human Calcium Sensing Receptor.
偶联物
形式
Liquid
浓度
0.55 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792284
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (93%), Rat (94%), Dog (95%), Cat (95%), Pig (95%), Bovine (95%).
Positive Control: 293T, A431, H1299, HeLa, mouse brain, mouse placenta.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ca sensing receptor; calcium-sensing receptor; CaR; CaSR; CaSR antibody; cation sensing receptor; Extracellular calcium-sensing receptor; G protein coupled receptor, family C, group 2, member A; G protein-coupled receptor, family C, group 2, member A; parathyroid Ca(2+)-sensing receptor 1; Parathyroid cell calcium-sensing receptor; Parathyroid cell calcium-sensing receptor 1; PCaR1
基因别名: CAR; CASR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1
UniProt ID: (Human) P41180, (Mouse) Q9QY96
Entrez Gene ID: (Human) 846, (Mouse) 12374
ossification
detection of calcium ion
cellular calcium ion homeostasis
G-protein coupled receptor signaling pathway
chemosensory behavior
anatomical structure morphogenesis
calcium ion import
calcium ion transport
signal transduction
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
JNK cascade
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of insulin secretion
positive regulation of ATPase activity
vasodilation
positive regulation of vasoconstriction
branching morphogenesis of an epithelial tube
positive regulation of positive chemotaxis
regulation of calcium ion transport
positive regulation of calcium ion import
