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Alomone Labs, LTD
Calcium Sensing Receptor (extracellular) Polyclonal Antibody
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Calcium Sensing Receptor (extracellular) Antibody (ACR-004-200UL) in ICC/IF
Expression of CaSR in rat C6 cells - Cell surface detection of CaSR in live intact rat glioma C6 cells. A. Extracellular staining of cells using Anti-Calcium SensingReceptor (extracellular) Antibody (#ACR-004), (1:50), followed by Alexa-555-conjugated goat- Anti-rabbit secondary Antibody . B. Nuclear fluorescence staining of cells using Hoechst 33342. C. Merged images of panels A and B.
产品信息
ACR-004-200UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)DDYG RPGIE KFREE, corresponding to amino acid residues 216-229 of human CaSR, Extracellular, N-terminus
偶联物
形式
Lyophilized
浓度
0.75 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ca sensing receptor; calcium-sensing receptor; Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism); Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); CaR; CaSR; CaSR antibody; cation sensing receptor; Extracellular calcium-sensing receptor; G protein coupled receptor, family C, group 2, member A; G protein-coupled receptor, family C, group 2, member A; parathyroid Ca(2+)-sensing receptor 1; Parathyroid cell calcium-sensing receptor; Parathyroid cell calcium-sensing receptor 1; PCaR1
基因别名: CAR; CASR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1
UniProt ID: (Human) P41180, (Rat) P48442, (Mouse) Q9QY96
Entrez Gene ID: (Human) 846, (Rat) 24247, (Mouse) 12374
ossification
detection of calcium ion
cellular calcium ion homeostasis
G-protein coupled receptor signaling pathway
chemosensory behavior
anatomical structure morphogenesis
calcium ion import
response to ischemia
calcium ion transport
apoptotic process
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
JNK cascade
positive regulation of cell proliferation
response to metal ion
positive regulation of gene expression
response to organic cyclic compound
positive regulation of insulin secretion
positive regulation of ATPase activity
cellular response to hepatocyte growth factor stimulus
vasodilation
positive regulation of vasoconstriction
branching morphogenesis of an epithelial tube
positive regulation of positive chemotaxis
response to calcium ion
regulation of calcium ion transport
fat pad development
cellular response to vitamin D
cellular response to glucose stimulus
cellular response to low-density lipoprotein particle stimulus
cellular response to hypoxia
response to fibroblast growth factor
positive regulation of calcium ion import
cellular response to peptide
signal transduction
