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Calmyrin Antibody (PA5-27284) in IHC (P)
Calmyrin Polyclonal Antibody detects CIB1 protein at cytoplasm on human lung carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded lung carcinoma. Calmyrin Polyclonal Antibody (Product # PA5-27284) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-27284
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 42 and 191 of Human CIB1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2544760
产品详细信息
Recommended positive controls: A431.
Predicted reactivity: Mouse (97%), Rat (98%), Zebrafish (80%), Sheep (97%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alphabeta, which may implicate this protein as a regulatory molecule for alphabeta.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium and integrin binding 1 (calmyrin); Calcium and integrin-binding protein 1; Calcium- and integrin-binding protein; Calmyrin; CIB; CIBP; DNA-dependent protein kinase interacting protein; DNA-PK interaction protein; DNA-PKcs-interacting protein; Kinase-interacting protein; KIP; SIP2-28; SNK-interacting protein 2-28; testicular secretory protein Li 9
基因别名: CIB; CIB1; CIBP; KIP; KIP1; PRKDCIP; SIP2-28
UniProt ID: (Human) Q99828
Entrez Gene ID: (Human) 10519
angiogenesis
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
positive regulation of cell-matrix adhesion
response to ischemia
double-strand break repair
apoptotic process
cellular response to DNA damage stimulus
negative regulation of microtubule depolymerization
endomitotic cell cycle
cell adhesion
spermatid development
positive regulation of cell proliferation
negative regulation of cell proliferation
negative regulation of neuron projection development
platelet formation
positive regulation of cell growth
positive regulation of cell migration
cytoplasmic microtubule organization
positive regulation of cell adhesion mediated by integrin
thrombopoietin-mediated signaling pathway
regulation of cell proliferation
negative regulation of apoptotic process
positive regulation of catalytic activity
negative regulation of megakaryocyte differentiation
positive regulation of NF-kappaB transcription factor activity
cell division
regulation of cell division
negative regulation of protein kinase B signaling
positive regulation of ERK1 and ERK2 cascade
positive regulation of calcineurin-NFAT signaling cascade
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
negative regulation of protein serine/threonine kinase activity
positive regulation of protein serine/threonine kinase activity
positive regulation of establishment of protein localization to plasma membrane
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of protein targeting to membrane
extrinsic apoptotic signaling pathway
positive regulation of substrate adhesion-dependent cell spreading
cellular response to nerve growth factor stimulus
positive regulation of male germ cell proliferation
