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产品信息
PA5-69533
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the N-terminal region of rat Calmyrin
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2690457
产品详细信息
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
靶标信息
The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alphabeta, which may implicate this protein as a regulatory molecule for alphabeta.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calcium and integrin-binding protein 1; calcium- and integrin-binding protein; Calmyrin; CIB; DNA-PKcs-interacting protein; Kinase-interacting protein; KIP
基因别名: Cib; Cib1; Kip; Prkdcip; Sip2-28
UniProt ID: (Rat) Q9R010
Entrez Gene ID: (Rat) 81823
angiogenesis
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
positive regulation of cell-matrix adhesion
response to ischemia
apoptotic process
cellular response to DNA damage stimulus
negative regulation of microtubule depolymerization
endomitotic cell cycle
cell adhesion
spermatid development
positive regulation of cell proliferation
negative regulation of cell proliferation
negative regulation of neuron projection development
platelet formation
positive regulation of cell growth
positive regulation of cell migration
cytoplasmic microtubule organization
positive regulation of cell adhesion mediated by integrin
thrombopoietin-mediated signaling pathway
regulation of cell proliferation
negative regulation of apoptotic process
positive regulation of catalytic activity
negative regulation of megakaryocyte differentiation
positive regulation of NF-kappaB transcription factor activity
cell division
regulation of cell division
negative regulation of protein kinase B signaling
positive regulation of ERK1 and ERK2 cascade
positive regulation of calcineurin-NFAT signaling cascade
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
positive regulation of protein serine/threonine kinase activity
positive regulation of establishment of protein localization to plasma membrane
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of protein targeting to membrane
positive regulation of substrate adhesion-dependent cell spreading
cellular response to nerve growth factor stimulus
positive regulation of male germ cell proliferation
