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Immunogen sequence: WELDEVNYAE QLQEEKVSED DMDQDFLHLF KIVAGEGKEI GVYELQRLLN RMAIKFKSFK TKGFGLDACR CMINLMDKDG SGK
The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Calcium-activated neutral proteinase 11; Calpain-11; CANP 11; HIP2; LIG
基因别名: calpain11; CAPN11
UniProt ID: (Human) Q9UMQ6
Entrez Gene ID: (Human) 11131