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Calpain S1 Antibody (PA5-117054) in IHC (P)
Immunohistochemistry analysis of Calpain S1 in paraffin-embedded human esophageal cancer. Samples were incubated with Calpain S1 Polyclonal antibody (Product # PA5-117054) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-117054
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 69-268 of human Calpain small subunit 1 (NP_0017401)
偶联物
形式
Liquid
浓度
1.05 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901684
产品详细信息
Positive Samples: BT-474, U-251MG, SKOV3, Mouse lung, Mouse heart, Mouse spleen, Rat lung
Immunogen sequence: ISEAAAQYNP EPPPPRTHYS NIEANESEEV RQFRRLFAQL AGDDMEVSAT ELMNILNKVV TRHPDLKTDG FGIDTCRSMV AVMDSDTTGK LGFEEFKYLW NNIKRWQAIY KQFDTDRSGT ICSSELPGAF EAAGFHLNEH LYNMIIRRYS DESGNMDFDN FISCLVRLDA MFRAFKSLDK DGTGQIQVNI QEWLQLTMYS
靶标信息
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 30K; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease, small subunit; calpain 4; calpain 4, small subunit (30K); Calpain regulatory subunit; Calpain small subunit 1; calpain, small polypeptide; calpain, small subunit 1; CANP small subunit; CDPS; CSS1; small pol
基因别名: CALPAIN4; CANP; CANPS; Capa-4; Capa4; CAPN4; CAPNS; CAPNS1; CDPS; CSS1; D7Ertd146e
UniProt ID: (Human) P04632, (Mouse) O88456, (Rat) Q64537
Entrez Gene ID: (Human) 826, (Mouse) 12336, (Rat) 29156
