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NeoBiotechnologies
Calprotectin/MRP14/S100A9/Calgranulin B Monoclonal Antibody (S100A9, 1075)
产品信息
6280-MSM5-P1ABX
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
S100A9, 1075
抗原
Recombinant human S100A9 protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
S100A9 (MRP-14) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BM-009; calgranulin B; Calgranulin-B; Calprotectin L1H subunit; DKFZp686B04128; intracellular calcium-binding protein (MRP14); Leukocyte L1 complex heavy chain; Macrophage; Migration inhibitory factor-related protein 14; Monocyte; MRP-14; MRP15; MRP16; Myeloid-related protein 14; p14; Protein S100-A9; S100 A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B)
基因别名: 60B8AG; CAGB; CFAG; CGLB; L1AG; LIAG; MAC387; MIF; MRP14; NIF; P14; S100A9
UniProt ID: (Human) P06702, (Rat) P50116
Entrez Gene ID: (Human) 6280, (Rat) 94195
cytokine production
leukocyte migration involved in inflammatory response
positive regulation of peptide secretion
regulation of translation
autophagy
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
signal transduction
cell-cell signaling
astrocyte development
positive regulation of blood coagulation
positive regulation of cell growth
neutrophil chemotaxis
actin cytoskeleton reorganization
sequestering of zinc ion
chemokine production
peptidyl-cysteine S-trans-nitrosylation
defense response to bacterium
innate immune response
regulation of integrin biosynthetic process
positive regulation of inflammatory response
defense response to fungus
positive regulation of NF-kappaB transcription factor activity
regulation of cytoskeleton organization
neutrophil aggregation
cellular oxidant detoxification
positive regulation of intrinsic apoptotic signaling pathway
chronic inflammatory response
response to zinc ion
leukocyte chemotaxis
response to lipopolysaccharide
response to ethanol
