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Carbonic Anhydrase II Antibody (PA5-89803) in WB
Western blot analysis of Carbonic Anhydrase II in extracts of various cell lines. Samples were incubated with Carbonic Anhydrase II Polyclonal antibody (Product # PA5-89803) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
产品信息
PA5-89803
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human Carbonic Anhydrase 2 (CA2) (NP_0000581)
偶联物
形式
Liquid
浓度
2.23 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805782
产品详细信息
Immunogen sequence: MSHHWGYGKH NGPEHWHKDF PIAKGERQSP VDIDTHTAKY DPSLKPLSVS YDQATSLRIL NNGHAFNVEF DDSQDKAVLK GGPLDGTYRL IQFHFHWGSL DGQGSEHTVD KKKYAAELHL VHWNTKYGDF GKAVQQPDGL AVLGIFLKVG SAKPGLQKVV DVLDSIKTKG KSADFTNFDP RGLLPESLDY WTYPGSLTTP PLLECVTWIV LKEPISVSSE QVLKFRKLNF NGEGEPEELM VDNWRPAQPL; Positive Samples: HL-60, 293T, Mouse kidney, Mouse spleen, Mouse lung; Cellular Location: Cell membrane, Cytoplasm
靶标信息
CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CA II; CA-II; CAC; Carbonate dehydratase II; Carbonic anhydrase 2; carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; carbonic dehydratase; Cyanamide hydratase CA2; epididymis luminal protein 76; epididymis secretory protein Li 282
基因别名: AI131712; CA-II; CA2; CAC; CAII; Car-2; Car2; HEL-76; HEL-S-282; Ltw-5; Lvtw-5
UniProt ID: (Human) P00918, (Mouse) P00920
Entrez Gene ID: (Human) 760, (Mouse) 12349
morphogenesis of an epithelium
one-carbon metabolic process
regulation of pH
carbon dioxide transport
positive regulation of synaptic transmission, GABAergic
positive regulation of cellular pH reduction
angiotensin-activated signaling pathway
regulation of anion transport
positive regulation of osteoclast differentiation
positive regulation of bone resorption
secretion
regulation of intracellular pH
positive regulation of dipeptide transmembrane transport
regulation of chloride transport
kidney development
response to pH
response to zinc ion
bicarbonate transport
odontogenesis of dentin-containing tooth
response to estrogen
response to steroid hormone
cellular response to fluid shear stress
