NeoBiotechnologies

Carboxypeptidase A1/CPA1 Monoclonal Antibody (CPA1, 2713)

Carboxypeptidase A1/CPA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Carboxypeptidase A1/CPA1 Antibody (1357-MSM3-P1ABX) in IHC (P)

Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human pancreas using Carboxypeptidase A1, CPA1 Monoclonal Antibody (Product # 1357-MSM3-P1ABX).

Carboxypeptidase A1/CPA1 Antibody in Western Blot (WB)

Carboxypeptidase A1/CPA1 Antibody in Peptide array (ARRAY)

Carboxypeptidase A1/CPA1 Antibody in SDS-PAGE (SDS-PAGE)

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产品信息

1357-MSM3-P1ABX

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

肽阵列 (Array)

Assay-dependent

产品规格

种属反应

Dog, Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

CPA1, 2713

抗原

Recombinant full-length human CPA1 protein

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C or -80°C if preferred

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

靶标信息

CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.

仅用于科研。不用于诊断过程。未经明确授权不得转售。